POVIDONE IODINE+ORNIDAZOLE
About
ORNIDAZOLE+POVIDONE IODINE belongs to the class of medications called 'antiseptic and disinfectant' primarily used to treat and prevent skin infections in minor burns, lacerations (deep cuts in the skin), cuts, and abrasions (the first layer of skin is scraped off). It also helps to treat infections of the lining of the mouth and throat, such as gingivitis (inflammation of the gums) and mouth ulcers. ORNIDAZOLE+POVIDONE IODINE is also used in infection control during insertion and care of urinary catheters, circumcision (removal of the foreskin from the human penis), suture removal and dressing changes.
ORNIDAZOLE+POVIDONE IODINE is a combination drug containing Povidone-Iodine and Ornidazole. Povidone Iodine works by inhibiting the growth of infection-causing microbes. As a small molecule, iodine in ORNIDAZOLE+POVIDONE IODINE can easily penetrate microorganisms and oxidizes essential proteins, nucleotides, and fatty acids, leading to cell death. Ornidazole inhibits protein synthesis and leads to cell death, thereby killing the bacteria. Collectively, both treat cuts, wounds and infections.
ORNIDAZOLE+POVIDONE IODINE is for external use only. ORNIDAZOLE+POVIDONE IODINE has common side effects, as every medicine does. These include local swelling, itchiness, redness, small blisters, and irritation at the application site. These side effects gradually resolve during the treatment and do not require medical attention.
Brief your medical history to the doctor if you are allergic to iodine or povidone. Let your doctor know if you have an overactive thyroid gland (hyperthyroidism) or thyroid diseases, liver, and kidney problems. Please tell your doctor if you are undergoing lithium therapy or radioactive iodine treatment. ORNIDAZOLE+POVIDONE IODINE should not be used before or after radioiodine scintigraphy or radioiodine treatment of thyroid carcinoma. Using ORNIDAZOLE+POVIDONE IODINE during breastfeeding may increase the iodine levels in the breastmilk, which can cause hypothyroidism in breastfed infants. ORNIDAZOLE+POVIDONE IODINE can cause excessive iodine absorption with its vaginal use; hence avoid douching (washing) with ORNIDAZOLE+POVIDONE IODINE and iodine-containing tampons during breastfeeding. Please consult your doctor if you are pregnant or planning to conceive before using ORNIDAZOLE+POVIDONE IODINE since it can affect the unborn baby.
Uses of POVIDONE IODINE+ORNIDAZOLE
Medicinal Benefits
ORNIDAZOLE+POVIDONE IODINE is an antiseptic and disinfectant used to treat and prevent skin infections in minor burns, lacerations (deep cuts in the skin), cuts, and abrasions (the first layer of skin is scraped off). It helps treat infections of the lining of the mouth and throat, such as gingivitis (inflammation of the gums) and mouth ulcers. ORNIDAZOLE+POVIDONE IODINE is also used in infection control during insertion and care of urinary catheters, circumcision (removal of the foreskin from the human penis), suture removal and dressing changes. It works by inhibiting the growth of infection-causing microbes. ORNIDAZOLE+POVIDONE IODINE is effective against bacteria (Gram-positive and Gram-negative, including antibiotic-resistant and antiseptic-resistant strains), fungi, viruses, and protozoa. ORNIDAZOLE+POVIDONE IODINE is used in degerming (physical removal of microbes), stasis ulcers (wound on the leg or ankle due to damaged veins), decubitus ulcers (bed sores), and the umbilical area. It is also used for degerming intravenous devices in blood transfusions, hyperalimentation (artificial supply of nutrients), cutdowns, and central venous lines.
Directions for Use
Storage
Side Effects of POVIDONE IODINE+ORNIDAZOLE
- Local swelling
- Itchiness
- Redness
- Small blisters
- Irritation at the application site
- Swelling of the skin and mucosa
In-Depth Precautions and Warning
Drug Warnings
Do not use ORNIDAZOLE+POVIDONE IODINE if you are allergic to povidone-iodine. Let your doctor know if you have an overactive thyroid gland (hyperthyroidism), any other thyroid diseases, or liver and kidney problems since the usage of ORNIDAZOLE+POVIDONE IODINE can cause iodine absorption into the body. This iodine absorption may lead to a rapid heartbeat (tachycardia) and restlessness, imbalance of electrolytes, abnormal blood concentration (osmolarity), and abnormal kidney function (renal impairment). Please tell your doctor if you are undergoing any lithium therapy or radioactive iodine treatment. ORNIDAZOLE+POVIDONE IODINE should not be used before or after radioiodine scintigraphy or radioiodine treatment of thyroid carcinoma. Using ORNIDAZOLE+POVIDONE IODINE during breastfeeding may increase the iodine levels in the breastmilk, which can cause hypothyroidism in breastfed infants. ORNIDAZOLE+POVIDONE IODINE can cause excessive iodine absorption with its vaginal use; hence avoid douching (washing) with ORNIDAZOLE+POVIDONE IODINE and iodine-containing tampons during breastfeeding. Please consult your doctor if you are pregnant or planning to conceive before using the ORNIDAZOLE+POVIDONE IODINE since it can affect the unborn baby.
Drug Interactions
Drug-Drug Interactions: ORNIDAZOLE+POVIDONE IODINE may interact with other antiseptics and products containing enzymatic components, alkali, mercury, silver, hydrogen peroxide, tannic acid, taurolidine, pain killers (aspirin, ibuprofen), antibiotic (azithromycin, sulfamethoxazole, trimethoprim), corticosteroids (dexamethasone), anti-diabetic (metformin), bronchodilator (albuterol), and diuretics (furosemide).
Drug-Food Interactions: No interaction found/established.
Drug-Disease Interactions: Before taking ORNIDAZOLE+POVIDONE IODINE, let your doctor know if you have any allergic reactions to iodine or povidone, overactive thyroid gland (hyperthyroidism) or any other thyroid diseases, liver, and kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
safe if prescribedNo interaction found/established.
Pregnancy
cautionPlease consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionConsult your doctor; there is no substantial research yet on using ORNIDAZOLE+POVIDONE IODINE in breastfeeding/nursing mothers.
Driving
safe if prescribedORNIDAZOLE+POVIDONE IODINE is generally safe to use before driving. However, if you notice any side effects like dizziness or burning sensation in the affected areas, avoid driving and operating machinery until you feel better.
Liver
cautionInform your doctor before receiving the ORNIDAZOLE+POVIDONE IODINE if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionInform your doctor before receiving the ORNIDAZOLE+POVIDONE IODINE if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Children
safe if prescribedYour doctor will prescribe ORNIDAZOLE+POVIDONE IODINE depending on your child's severity of infection or wounds.
Habit Forming
Diet & Lifestyle Advise
- Use mild soap while taking baths and prefer warm baths.
- Avoid harsh products on your skin.
- Do not scratch or pick your skin to avoid getting the affected area infected.
- Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
- Do not walk barefoot at places like gym showers to prevent bacterial infections.
Special Advise
- Thyroid function monitoring (thyroid function tests like T3, T4 and TSH levels) is recommended in patients to check on overactive thyroid gland function, which is possible due to iodine absorption into the body.
- Regular monitoring of electrolytes is necessary since iodine is possibly absorbed into the body and causes an imbalance of electrolytes.
- It is better to take an electrocardiograph (ECG) if you notice rapid heartbeat (tachycardia).
- It is advised to take a blood osmolarity test since ORNIDAZOLE+POVIDONE IODINE may cause iodine absorption leading to abnormal blood concentration.
- Kidney function monitoring is advised in patients since ORNIDAZOLE+POVIDONE IODINE may affect kidney disease patients with renal impairment.
Patients Concern
Disease/Condition Glossary
Skin infection: Skin infection can occur when the skin is broken, cut or wounded. This skin infection allows pathogenic microorganisms to enter and invade the tissues surrounding the wound.
FAQs
ORNIDAZOLE+POVIDONE IODINE is used to treat and prevent skin infections in minor burns, lacerations (deep cuts in the skin), cuts, and abrasions (the first layer of skin is scraped off). It also helps to treat infections of the lining of the mouth and throat, such as gingivitis (inflammation of the gums) and mouth ulcers.
ORNIDAZOLE+POVIDONE IODINE is a combination drug containing antiseptic and antibacterial that treats skin infections of wounds and cuts. ORNIDAZOLE+POVIDONE IODINE works by inhibiting the growth of infection-causing microbes. As a small molecule, Iodine in ORNIDAZOLE+POVIDONE IODINE can easily penetrate microorganisms and oxidizes essential proteins, nucleotides, and fatty acids, leading to cell death.
ORNIDAZOLE+POVIDONE IODINE should be used with proper caution and doctor consultation if you have any liver disease, kidney disease, goitre (abnormal enlargement of the thyroid gland), thyroid nodules or other non-acute thyroid diseases. Please tell your doctor if you are undergoing any lithium therapy or treatment involving radioactive iodine.
ORNIDAZOLE+POVIDONE IODINE is not recommended for use if you are undergoing any lithium therapy or treatment involving radioactive iodine. ORNIDAZOLE+POVIDONE IODINE should not be used before or after radioiodine scintigraphy or radioiodine treatment of thyroid carcinoma. In such conditions, please consult your doctor before using ORNIDAZOLE+POVIDONE IODINE.
ORNIDAZOLE+POVIDONE IODINE may interfere with thyroid function tests due to iodine absorption. Please ask your doctor before starting ORNIDAZOLE+POVIDONE IODINE if you have any history of thyroid problems. A ORNIDAZOLE+POVIDONE IODINE can also show false-positive lab results, such as tests with toluidine or gum guaiac, to determine haemoglobin or glucose in the stool or the urine.
If you miss a dose of ORNIDAZOLE+POVIDONE IODINE, skip it and continue with your regular schedule. Do not double the dose.
